Spironolactone Antisterone,best quality Aldactone,Antisterone,spirolactone,52-1-7

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Spironolactone Antisterone
Technical features

Description:

Spironolactone Antisterone




Spironolactone

Alias: Aldactone;Antisterone;spirolactone
CAS NO: 52-1-7
Einecs No: 200-133-6
MF: C24H32O4S
MW: 416.58

Purity: 98.0%
Appearance:  White or white crystal powder of fine;Slightly bitter taste, odourless or slightly mercaptan odor.Insoluble in water, soluble in ethanol, soluble in benzene or ethyl acetate.

Usage: Spironolactone is competitive inhibition of aldosterone drugs, drug itself is not active, role is diuresis and endogenous competitive aldosterone antagonist and happen, belongs to the potassium diuretics.

 

Specifications:

Test ItemsSpecificationTest Results
AppearanceAlmost white crystalline powderAlmost white crystalline powder
IdentificationMeet the requirementsMeet the requirements
Melting rangeBetween 198℃ and 209205.0~207.0
Specific rotationBetween -33° and -37°-35°
Loss on dryingNot more than 0.5%0.2%
Limit of mercapto compoundsMeet the requirementsMeet the requirements
Ordinary impuritiesMeet the requirementsMeet the requirements
Organic volatile impuritiesMeet the requirementsMeet the requirements
Assayon the dried basisBetween 97.0% and 103.0%98.99%
ConclusionMeet the requirements of USP29

 




Specifications:

Test ItemsSpecificationTest Results
Appearance Almost white crystalline powderAlmost white crystalline powder
Identification Meet the requirementsMeet the requirements
Melting rangeBetween 198and 209205.0~207.0
Specific rotation Between -33° and -37°-35°
Loss on drying Not more than 0.5%0.2%
Limit of mercapto compoundsMeet the requirementsMeet the requirements
Ordinary impurities Meet the requirementsMeet the requirements
Organic volatile impuritiesMeet the requirementsMeet the requirements
Assayon the dried basisBetween 97.0% and 103.0%98.99%
ConclusionMeet the requirements of USP29


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