Another use of Masteron which has become more common lately is combination with Trenbolone Acetate. Unlike combination with Dianabol Methandienone or Anadrol Oxymetholone, there is only an additive effect, not a synergistic effect. However, including Masteron allows a lower trenbolone dosage while achieving very similar or equal physique benefit with less potential for trenbolone-specific side effects of night-sweats, increased tendency to aggression, and/or insomnia.
Masteron also is useful in combination with testosterone for self-prescribed hormone-replacement therapy (HRT.) For example, 100 mg/week each of Masteron and testosterone can be superior for physique benefits to 200 mg/week testosterone alone, while being milder in side effects due to lower resulting levels of estradiol (estrogen) and Muscle powder DHT.
I don’t recommend using Masteron alone for a steroid cycle or HRT because estradiol levels typically fall too low when this is done. Inclusion of for example at least 100 mg/week testosterone, at least 10 mg/day Dianabol Methandienone, or at least 700 IU/week total HCG will maintain normal estradiol levels during a Masteron-only cycle, should one wish to do this.
As a propionate ester, Masteron has a half-life of probably two days and therefore is preferably injected at least every other day, and more preferably daily. An enanthate ester version having a half-life of probably 5 days has become available. This version of Masteron may be injected as infrequently as twice per week.
The traditional (Masteron Dromostanolone Propionate) form of Masteron is also advantageous for brief cycles or for use at the end of a longer cycle, giving quick transition from high, anabolically-effective blood levels to levels sufficiently low to allow recovery of natural testosterone production.
Very simply, Masteron does very well what it’s supposed to do, and has as mild a side-effect profile as is possible for an anabolic steroid. I have never known anyone to be disappointed with this steroid, provided sufficient dosing was used.